G protein-coupled receptors (GPCRs) form one of the largest drug target families, with 516 approved drugs targeting GPCRs. They play a central role in cellular signalling pathways, including neurotransmission, immune response and metabolic regulation, making them key targets for therapeutic intervention.
However, GPCR research faces constraints due to the complexity of receptor signalling mechanisms and the challenge of maintaining data integrity, requiring increasingly advanced technologies and highly accurate assays.
Download this exclusive eBook from Eurofins to learn more about:
• GPCR biology and the development of new therapeutics
• Why you should measure signalling bias in your molecules
• Employing assay “volume control” to unveil efficacies in allosteric lead molecules
• How to unlock orphan GPCRs with a forward trafficking approach
• Accelerating development of GLP-1 & GLP-2 therapeutics
