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title: Embedding quality into cell line development through the application of an innovative picodroplet-based single cell sorter
description: Embedding quality into cell line development through the application of an innovative picodroplet-based single cell sorter webinar supported by Sphere Fluidics.
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Webinar

Embedding quality into cell line development through the application of an innovative picodroplet-based single cell sorter

 

 

 

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Generation of a highly expressing, regulatory acceptable clonal cell line is the first key activity in the development of a biopharmaceutical. Cell line development is labour intensive, time consuming and costly, and is subject to stringent regulations to ensure patient safety.   
   
All cell lines used to produce clinical batches of biopharmaceuticals are required to conform to ICH5Q which requires that cell lines are demonstrated to have a traceable history, are clonal and their construction is fully documented.  
   
In this webinar  Dr Jonathan H. Dempsey, Managing Director of Dempsey Consulting and Founding Partner of Pathway Biopharma Consulting will describe the implementation of an innovative technology which provides a visual record of clonality, history and clone derivation and also allows for transfected pool enrichment resulting in highly expressing clones.   
   
A comparison of this instrument with existing methods and highlight benefits of traceability and speed from transfection to a clonal cell line will be presented.   
   
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