Combining human iPSC-derived neurons with multi-electrode array (MEA) assays can provide powerful insights into synaptic connectivity, network dynamics, and functional maturation. However, MEA experiments can be challenging, with small changes in cell culture conditions dramatically impacting results.

In this expert guide, bit.bio’s Field Applications Scientist shares key considerations for improving consistency, reducing variability, avoiding common pitfalls and supporting the generation of reliable electrophysiological data in long-term studies.

Download this guide to discover:

• Environmental optimisation to reduce contamination rates
• Precise timing protocols for plate preparation, cell seeding and long-term maintenance
• Quality control measures to identify and prevent costly experimental failures

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