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The regulation of cellular bioenergetics is recognised as a key driver of cancer cell proliferation. Identifying key pathways that modulate bioenergetic metabolism is a promising strategy for developing novel therapeutics for cancer treatment.

In this App Note you will learn:

  • How the Agilent Seahorse XF Real Time ATP rate assay provides a simple robust workflow that can identify metabolic targets for drug discovery.
  • How it can identify metabolic target pathways to be investigated during cancer drug discovery.
  • About the dedicated analytic software as a direct way to quantitate and compare the metabolic response of cancer cells to chemicals or genetic modification and differentiate mitochondrial and glycolytic energetic metabolism.

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