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In this scientific poster, just revealed at ISSCR 2023, you will discover:

  • How precision reprogramming generates consistent, functional human microglia (ioMicroglia) from iPSCs in just 10 days
  • Independent validation that ioMicroglia undergo phagocytosis of both E. coli particles and amyloid beta particles
  • Independent validation that ioMicroglia show a pro-inflammatory cytokine response to various disease-relevant stimuli
  • How ioMicroglia can form co-cultures with glutamatergic neurons to probe complex intercellular interactions in vitro

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Download the poster