The human body has the capacity to produce an array of specialized T cells, which provide unique responses to a diverse range of tumor cells and pathogens.

The modulation of T cells is an exciting prospect for the development of novel therapies for immuno-oncology –autoimmune applications, adoptive cell therapy and vaccine development.

This white paper provides an overview of the importance of understanding T Cell Biology, for building better therapeutics. The use of advanced flow cytometry to study the processes controlling T cell activation, killing and exhaustion, in cases of Patient to Patient Variability, BiTE antibody evaluation and CAR-T cell characterization, is discussed.

Read how the iQue^® 3 advanced flow cytometry platform, provides a rapid, high throughput solution to the study or monitoring of T cell function and phenotype, plus helps to identify early biomarkers or perform serological characterizations.